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KMID : 0351619630040010079
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Kyungpook Medical Journal
1963 Volume.4 No. 1 p.79 ~ p.85
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COMPARATIVE STUDY OF SKIN AND PRECIPITIN REACTION OF VARIOUS FRACTIONS OF CLONORCHIS SINENSIS BETWEEN MAN AND RABBIT
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崔東翊/Choi, Dong Wik
申大植/金正浣/金正萬/Sin, Dae Sik/Kim, Jung Wan/Kim Jung Man
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Abstract
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The alkali & acid soluble protein fractions and Polysaccharide fractions from the adult Clonorchissinesis of rabbit and man were employing the identical method, and further study was carried out in the skin and precipitin reaction in order to determine the best antigen among the fraction.
The results observed are summarized as follow:
Ⅰ. Skin reaction
1) There is no significant difference in positive rate and reactivity between man and experimental rabbit´s alkali soluble protein fraction and acid soluble protein fraction.
2) In the polysaccharide fracion, the positive rate of antigen fractionated from man´s Clonorchis sinesis is higher than antigen from rabbit.
3) The positive rate of antigen fractionated from man´s Clonorchis sinensis is 47.5%(38 cases among 80), whereas from antigen of rabbit, it is 6.1% (5 cases among 82) in the polysaccharide fraction remained acid media.
Ⅱ. Precipitin reaction
1) No apparent differences are observed in the titres of precipitin reactons freacionated from the alkali soluble protein & polysaccharide fraction, and also from the acid soluble protein and polysaccharide fraction of man and rabbit Clonrchis sinesis.
2) The titre of precipitn reaction is higher in the polysaccharide fraction in the case of serum of human patient, while it is higher in the protein fraction in the cases of rabbit serum.
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